No. 1 Choice of Pediatricians & Moms in US. The creamy, fast-acting formula of DESITIN Rapid Relief instantly forms a protective layer on your baby’s skin to soothe and relieve rash discomfort. This paraben-free, dermatologist-tested formula is also fragrance-free, so it is gentle enough to use at every diaper change. It goes smoothly and wipes off easily, making DESITIN Rapid Relief your trusted partner for treating diaper rash from the first signs.